Registration Dossier
Registration Dossier
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EC number: 201-800-4 | CAS number: 88-12-0
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.045 mg/L
- Assessment factor:
- 1 000
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.004 mg/L
- Assessment factor:
- 10 000
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 3 373 mg/L
- Assessment factor:
- 1
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.22 mg/kg sediment dw
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.02 mg/kg sediment dw
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.017 mg/kg soil dw
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Evaluating the short-term L(E)C50 values for n-Vinylpyrrolidone (nVP), those for fish and algae largely exceed the limit of 100 mg/L. For Daphnia only, an EC50 of < 100 mg/L was found: 45 mg/L. Further, nVP is readily biodegradable and long-term testing in Daphnia is waived. Substances that rapidly degrade can be quickly removed from the environment. While effects of such substances can occur, particularly in the event of an accidental spillage, they are localised and of short duration. According to Annex IX Column 2 of Regulation (EC) No 1907/2006, long-term toxicity testing is to be proposed if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. The hazard assessment of nVP reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment.
Conclusion on classification
n-Vinylpyrrolidone (nVP) is not classified as hazardous to the aquatic environment according to the criteria laid out in Regulation (EC) 1272/2008 or in Directive 67/548/EEC based ona 48 hour EC50 in invertebrates (Daphnia magna) of 45 mg/L (BASF, 1990), a 72 hour LC50 in freshwater fish (Oncorhynchus mykiss) of 976 mg/L (BASF, 1987), a 72 -hrEC50 of >1000 mg/L (algae), a LogKow of 0.4, and a BCF of 3.16 L/kg.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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