Registration Dossier
Registration Dossier
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EC number: 209-062-5 | CAS number: 554-13-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1973
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Only data from review article available.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Lithium Carbonate
- Author:
- Kiso to Rinsho
- Year:
- 1 973
- Bibliographic source:
- Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1-1960-7,1273,1973 (KSRNAM); via RTECS
Materials and methods
- Principles of method if other than guideline:
- Only data from review article available. No guideline or method indicated.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lithium carbonate
- EC Number:
- 209-062-5
- EC Name:
- Lithium carbonate
- Cas Number:
- 554-13-2
- Molecular formula:
- CH2O3.2Li
- IUPAC Name:
- dilithium carbonate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 525 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- According to the review article, the LD50 of lithium carbonate is 525 mg/kg bw after oral administration to rats.
- Executive summary:
According to the review article, the LD50 of lithium carbonate is 525 mg/kg bw after oral administration to rats. Thus, lithium carbonate has to be classified as cat. 4, H302 (harmful if swallowed) according to Regulation (EC) No 1272/2008 (CLP).
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