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EC number: 260-906-9 | CAS number: 57693-14-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) between 10 and 100 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 30.2 mg/L
Additional information
Two studies according to OECD guideline 202 are available, both conducted under static conditions for an exposure period of 48 h..
In one study, 5 concentrations were tested in the range of 6.25 to 100 mg/l, prepared with dilution water in a geometric series with a factor of 2. Twenty daphnids were exposed to each concentration level and the control.
Concentrations of test item were
analytically verified by HPLC-DAD at the start of the
exposure (0 h) and at the end of the exposure (48 h) of all
concentration levels and the control.
Concentrations of test
item were successfully maintained for
the duration of the test, thus endpoints
were assessed based on nominal concentrations of test item.
The validity criteria of the test guideline were fulfilled.
Effect levels after 48 h:
EC10 = 16.4 mg/l (95 % conf. limit 13.2 - 19)
EC50 = 30.2 mg/l (95 % conf. limit 27.1 - 33.7)
EC100 = 100 mg/l (not applicable)
NOEC = 12.5 mg/l (not applicable)
LOEC = 25 mg/l (not applicable)
In the second study, nominal concentrations tested were 10 / 18 / 32 / 58 / 100 and 180 mg/I, and a control without any additions. In all test concentrations, no alteration of the test substance was observed after 48 hours.
During the test, measured concentrations were in the range of 100 - 109 % of the nominal values. Therefore, under test conditions, the test article was sufficiently stable.
The reported results are related to the average analytical concentrations of the test article measured at the beginning and at the end of the test.
No immobilization and abnormal behaviour of daphnids was observed in the control.
Effect levels at 48 :
NOEC and EC0 = 10 mg/l
EC100 = 192 mg/l
EC50 = 79 mg/l.
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