Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 243-718-1 | CAS number: 20298-69-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Abiotic degradation:
Air:
Based on estimation with the QSAR model AopWin the substance undergoes in air rapid degradation after reaction with hydroxyl radicals with a DT50 value of 26.55 hours. No ozone reaction estimation could be made with AopWin. Verdox will not reach the stratosphere and is therefore not considered to be a long-range transported chemical in air. In addition, the substance does not have an ozone depletion potential because it does not contain halogens (EU CLP; EC 1272/2008 and its amendments).
Water:
Based on a study performed on Verdox, the half-life time at 25°C is 49 hours for pH 4, 7 and 9. It is concluded that the substance is hydrolytically unstable.
Biotic degradation:
In a screening study according to OECD TG 301F, 43% biodegradation was found after 28 days. Prolongation of this study to 60 and 61 days resulted in 61% and 62% biodegradation, respectively. Based on these findings Verdox is to be considered as not readily biodegradable.
Bioaccumulation:
Overall it can be concluded that Verdox has no bioaccumulation potential with an experimentally determined BCF value for fish of 203 L/kg, corresponding to 156 L/kg when converted to a standard fish lipid content of 5%. Based on this no bioaccumulation is expected (BCF <500).
The BCF in earthworms was estimated with the equation from Jager (1998) using the log Kow as input giving a value of 676 L/kg.
Transport and distribution:
The adsorption coefficient (Koc) of Verdox was determined in a HPLC screening test according to OECD Guideline 121. Under the conditions of the test, the log Koc of Verdox was determined at 3.12 (Koc of 1300 L/kg). This indicates that the substance will have a moderate potential to adsorb to sediment/soil.
A Henry's law constant of 103 Pa·m³/mol (at 12 °C) was calculated in EUSES. Based on this value Verdox will partition from water to air.
Based on Level III distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the CAS number 88-41-5 and the measured physico-chemical parameters, water solubility and log Kow as input, it is estimated that the majority of the substance released to the environment will partition mainly into soil (82%) and water (16%) with small amounts to sediment (0.4%) and air (2.1%).
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of substances in a Sewage Treatment Plant. The results of this model for Verdox show that the substance will not be degraded and that 56.9% of the substance will partition to air, 31.6% will partition to water and 11.5% to sewage sludge.
Additional information
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