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Environmental fate & pathways

Hydrolysis

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Endpoint:
hydrolysis
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Endpoint:
hydrolysis
Type of information:
other: Technical Discussion
Adequacy of study:
supporting study
Study period:
N/A
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from several peer reviewed sources.
Justification for type of information:
A discussion and report on the read across strategy is given as an attachment in IUCLID Section 13.
Reason / purpose:
read-across: supporting information
Qualifier:
no guideline followed
GLP compliance:
no
Remarks:
not applicable
Radiolabelling:
not specified
Conclusions:
Hydrolysis is a reaction in which a water molecule or hydroxide ion substitutes for another atom or group of atoms present in a chemical resulting in a structural change of that chemical. Potentially hydrolyzable groups include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters (Neely, 1985). The lack of a suitable leaving group renders compounds resistant to hydrolysis.

The chemical constituents that comprise hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) consist entirely of carbon and hydrogen and do not contain hydrolyzable groups. As such, they have a very low potential to hydrolyze. Therefore, this degradative process will not contribute to their removal from the environment.
Executive summary:

Hydrolysis is a reaction in which a water molecule or hydroxide ion substitutes for another atom or group of atoms present in a chemical resulting in a structural change of that chemical. Potentially hydrolyzable groups include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters (Neely, 1985). The lack of a suitable leaving group renders compounds resistant to hydrolysis.

The chemical constituents that comprise hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) consist entirely of carbon and hydrogen and do not contain hydrolyzable groups. As such, they have a very low potential to hydrolyze. Therefore, this degradative process will not contribute to their removal from the environment.

Description of key information

Hydrolysis is a reaction in which a water molecule or hydroxide ion substitutes for another atom or group of atoms present in a chemical resulting in a structural change of that chemical. Potentially hydrolyzable groups include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters (Neely, 1985). The lack of a suitable leaving group renders compounds resistant to hydrolysis.

The chemical constituents that comprise C14-C20 Aliphatics (2-30% Aromatics) consist entirely of carbon and hydrogen and do not contain hydrolyzable groups. As such, they have a very low potential to hydrolyze. Therefore, this degradative process will not contribute to their removal from the environment.

Key value for chemical safety assessment

Additional information

Hydrolysis is a reaction in which a water molecule or hydroxide ion substitutes for another atom or group of atoms present in a chemical resulting in a structural change of that chemical. Potentially hydrolyzable groups include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters (Neely, 1985). The lack of a suitable leaving group renders compounds resistant to hydrolysis.

The chemical constituents that comprise C14-C20 Aliphatics (2-30% Aromatics) consist entirely of carbon and hydrogen and do not contain hydrolyzable groups. As such, they have a very low potential to hydrolyze. Therefore, this degradative process will not contribute to their removal from the environment.