Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Obtained from a reliable handbook of chemical values

Data source

Reference
Reference Type:
review article or handbook
Title:
Exploring QSAR, hydrophobic, electronic, and steric constants, by Hansch C, Leo A, Hoekman D.
Author:
Heller SR
Year:
1995
Bibliographic source:
ACS Professional Reference Book. American Chemical Society, Washington DC

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
This data is obtained from a reputable handbook of values for physical - chemical properties. Methodology was not specified, but it is assumed to be based on methods found in existing guidelines. Current experience with handling this substance indicates that this data is valid.
Type of method:
other: (Q)SAR reported from Handbook; no method specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. -0.25
Temp.:
20 °C
pH:
ca. 7

Applicant's summary and conclusion

Conclusions:
The log of the octanol/water partition coefficient for HCN is -0.25 at 20 °C.