Registration Dossier
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EC number: 206-058-5 | CAS number: 298-12-4
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 18. May to 02. June 2009
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Harlan Laboratories Ltd., Quality Assurance GLP, Zelgliweg 1, 4452 Itingen, Switzerland
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of activated sludge:
wastewater treatment plant (ARA Ergolz II, Füllinsdorf / Switzerland) treating predominantly domestic wastewater
- Storage conditions:
room temperature
- Pretreatment:
The sludge was washed twice with tap water by centrifugation and the supernatant liquid phase was decanted. A homogenized aliquot of
the final sludge suspension was weighed, thereafter dried and the ratio of wet to dry weight was calculated
- Concentration of sludge:
30 mg dry material per liter - Duration of test (contact time):
- 14 d
- Initial conc.:
- 30.4 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 98
- St. dev.:
- 2.8
- Sampling time:
- 3 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Due to the fact that > 98 % of Glyoxylic Acid 50 % were degraded within the 10-d window of the incubation period, the test item can be classified as readily biodegradable under the conditions of this study.
- Executive summary:
In a Ready Biodegradability study (OECD 301 A) Glyoxylic Acid 50% was assessed over a 14 day period by the DOC die away test. The nominal test concentration was 30.4 mg/L. The test material attained > 98 % biodegradation after 3 and 10 days, respectively. The reference compound sodium benzoate showed a mean biodegradability of > 90 % within 7 days, thus confirming suitability of the activated sludge.
These results indicate that Glyoxylic Acid 50% is readily biodegradable under conditions of the test.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: IRCHA; Exp. AFNOR Norm T90 302
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: according to Norm T90 302
- Duration of test (contact time):
- 14 d
- Initial conc.:
- 39.27 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Reference substance:
- other: Glucose
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 99
- Sampling time:
- 3 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 95.5
- Sampling time:
- 7 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 98.1
- Sampling time:
- 14 d
- Results with reference substance:
- 3 days = 97.6 %
7 days = 92.2 %
14 days = 96.8 % - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Readily biodegradable
Referenceopen allclose all
Description of key information
> 98 % of Glyoxylic Acid 50 % were degraded within a 10-d incubation period and is therefore readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
In a Ready Biodegradability study (OECD 301 A) Glyoxylic Acid 50% was assessed over a 14 day period by the DOC die away test. The nominal test concentration was 30.4 mg/L. The test material attained > 98 % biodegradation after 3 and 10 days, respectively. These results indicate that Glyoxylic Acid 50% is readily biodegradable under conditions of the test.
The reference compound sodium benzoate showed a mean biodegradability of > 90 % within 7 days, thus confirming suitability of the activated sludge.
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