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Diss Factsheets

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the stability of the substance is not considered to be critical
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
22-01-1993
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Details on results:
Partition coefficient was not measurable as glyoxylic acid forms hemiacetal with n-octanol as shown by acidimetry and polarography.
Executive summary:

Partition coefficient was not measurable as glyoxylic acid forms hemiacetal with n-octanol as shown by acidimetry and polarography.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion