Registration Dossier
Registration Dossier
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EC number: 204-469-4 | CAS number: 121-44-8
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Since a NOEC value is not clearly specified, the study performed by Van Leeuwen et al. (1990) is not considered as relevant for the CSA.
Key value for chemical safety assessment
Additional information
Fish embryos of Salmo gairdneri (new name: Oncorhynchus mykiss) were used to investigate the chronic toxicity of triethylamine in a semi-static freshwater experiment (van Leeuwen et al., 1990). This early life stage test was conducted for 60 days. Test concentrations are not specified. Based on mortality the following nominal results are reported: LC50 (60d) = 137 mg/L, EC50 (60d) = 130 mg/L, and LOEC (60d) > 100 mg/L, respectively. Taking the body length into account a LOEC (60d) of 100 mg/L is given. A LOEC (60d) of 3.2 mg/L is the result concerning weight of the test organisms as basis for effect.
Furthermore, the long-term toxicity of the test substance was determined by evaluating fertilized eggs of Danio rerio, which were observed for 7 days (van Leeuwen et al., 1990). Test concentrations are not specified. Effects such as mortality rate, developmental changes and multiple effects
(integrated) were investigated at different mean test temperatures and pH values. The LC50 (7d) was determined as 180 mg/L. Based on the total embryotoxicity, the EC50 (7d) amounts to 53 mg/L while the LOEC (7d) is reported as 100 mg/L. Based on mortality, the LOEC (7d) amounts to 320 mg/L.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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