Registration Dossier
Registration Dossier
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EC number: 202-095-6 | CAS number: 91-76-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 value, respectively the NOEC, from the activated sludge respiration inhibition testing according to OECD guideline 209 has been used for the chemical safety assessment.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Different results from toxicity testing on micro-organisms are available. In first an OECD guideline 209 study with predominately domestic activated sludge showing a NOEC (3h) = 100 mg/L based on respiration rate as well as an EC50 (3h) > 1000 mg/L. In line with this results a second study according to a national guideline shows an EC20(4h) = 100 mg/L. As the latter result is from a publication of the German Commission on Evaluation of Hazardous Substances to Waters a comprehensive evaluation of the data quality is not possible. Therefore the results of the first study have been selected for the chemical safety assessment for the examination of effects on STP micro-organisms.
In addition, studies in single species have been also available. A growth inhibition study with Pseudomonas putida according to DIN 38412 showing an EC10 (18h) = 3.4 mg/L and an inhibition of photoluminescence study in accordance with guideline DIN 38412-L34 showing an EC50 = 210 mg/L. While for the growth inhibition study a full report was available and, in consequence, an evaluation of the quality was possible, for the latter study the published result by the KBwS was available only.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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