Registration Dossier
Registration Dossier
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EC number: 200-842-0 | CAS number: 75-12-7
Toxicity to other above-ground organisms
Administrative data
Link to relevant study record(s)
Description of key information
Two studies on tadpoles from Xenopus laevis and Rana bravipoda porosa were conducted. The determined LC50 and IC50 values respectively ranged from 4.3 to 12.8 g/l
Key value for chemical safety assessment
Additional information
The parameters studied in both of the tadpole studies demonstrate that formamide is not harmful to the test organisms.
| Reference | Parameter | Endpoint | Exposure time | value [mg/l] |
| Dresser et al. (1992) | mortality | LC50 | 96 hours | 11380 |
| Dresser et al. (1992) | malformation | EC50 | 96 hours | 12810 |
| Dresser et al. (1992) | mortality | NOEC | 96 hours | 5670 - 11340 |
| Dresser et al. (1992) | malformation | NOEC | 96 hours | 5670 - 8500 |
| Dresser et al. (1992) | body length | NOEC | 96 hours | 8500 - 11340 |
| Nishiuchi (1984) | mortality | LC50 | 48 hours | 4300 |
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