Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
1 400 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
7 360 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
3 271 mg/kg bw

Additional information

Oral LD50 determined in guinea pigs (Smyth 1941);

Dermal LD 50 was determined in rabbits (Carpenter 1956); the value was 3.56 mL/kg which corresponded to 3271 mg/kg (density of 0.919 g/mL at 25 °C);

Justification for classification or non-classification

Inhalative LC50 was determined in female rats 7,36 mg/l/ 8 h of exposure (Pozzani 1959); according to the "OPINION OF THE COMMITTEE FOR RISK ASSESSMENT ON A DOSSIER PROPOSING HARMONISED CLASSIFICATION AND LABELLING AT COMMUNITY LEVEL, 9 March 2011", Committee for Risk Assessment RAC, ECHA/RAC/CLH-O-0000001587-67-01/F, the substance has to be classified as Acute Tox. 3, H331;