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Long-term toxicity to fish

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The long-term toxicity for fish endpoint is addressed by read across to long-term toxicity for aquatic invertebrates (Daphnia magna). Read across to OLBOs has been applied for the long-term toxicity to aquatic invertebrates endpoint, which is justified based on similarities in composition and physical/chemical properties between slack wax and OLBOs. Toxic effects of hydrocarbons are primarily caused by narcosis, and occur in a narrow range of molar concentrations across aquatic taxa; hence, read across between species is justified.

Results of computer modelling to estimate aquatic chronic toxicity of slack wax in a 28 -day freshwater fish study show no chronic toxicity to freshwater fish at or below its maximum attainable water solubility (Redman et al., 2010b). This supports the applied interspecies read across.