Registration Dossier

Administrative data

Endpoint:
epidemiological data
Type of information:
other: The odour thresholds and irritation levels of approximately 450 chemicals were taken from the industrial hygiene literature and other compilations of odour threshold data and gathered together in one listing.
Adequacy of study:
weight of evidence
Study period:
Not reported
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP, non-guideline, published in peer reviewed literature, notable limitations in design and/or reporting but contributes to a weight of evidence assessment

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1986
Report Date:
1986

Materials and methods

Study type:
other: Compilation of data taken from the industrial hygiene literature and other compilations of odour threshold data.
Endpoint addressed:
respiratory irritation
other: odour thresholds
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
The odour thresholds and any threshold levels of irritation to humans for approximately 450 chemicals were taken from the industrial hygiene literature and other compilations of odour threshold data and gathered together in one listing.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
Constituent
Test material form:
not specified
Details on test material:
no data

Method

Type of population:
not specified
Ethical approval:
not applicable
Details on study design:
METHOD OF DATA COLLECTION
- Type: Gathered from the industrial hygiene literature and other compilations of odour threshold data.

OTHER DESCRIPTIVE INFORMATION ABOUT STUDY:
- Odour thresholds recorded as a concentration range (lowest to highest reported).
- The concentration where any irritation begins was also recorded.
- Subjective descriptions (if available) were recorded.
- If an American Conference of Governmental Industrial Hygienists Threshold Limit Value (TLV) had been determined, this was recorded.

All the above were entered into a data base programme for manipulation.
Exposure assessment:
not specified
Statistical methods:
Not applicable

Results and discussion

Results:
Odour threshold low = 0.0240 mg/m^3
Odour threshold high = 20.0000 mg/m^3
Description of odour = almonds
Irritating concentration = 48.00 mg/m^3

Applicant's summary and conclusion

Conclusions:
The odour threshold range for furfural was 0.0240 - 20.0000 mg/m^3
Description of odour = almonds
The irritating concentration for furfural was 48.00 mg/m^3
Executive summary:

The odour thresholds and irritation levels of approximately 450 chemicals were taken from the industrial hygiene literature and other compilations of odour threshold data and gathered together in one listing.

The odour threshold range for furfural was 0.0240 - 20.0000 mg/m^3. The odour of furfural was described as almonds. The irritating concentration for furfural was 48.00 mg/m^3.