Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given Limited information concerning test conditions and/or experimental methods

Data source

Reference
Reference Type:
publication
Title:
The determination of the irritancy potential of surfactants using various methods of assessment.
Author:
Ciuchta, H.P. and Dodd, K.T.
Year:
1978
Bibliographic source:
Drug Chem Toxicol 1, 305-324

Materials and methods

Type of study / information:
Type: other: upper respiratory tract irritation

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

The RD50 value (i.e. a concentration producing a 50% decrease in 

respiration rate) was given with 135.3 ug/L, while data concerning 

systemic effects were not reported.

Applicant's summary and conclusion