4,4'-Methylenediphenyl diisocyanate, oligomers

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising liquids

Type of information:

other: exemption statement

Adequacy of study:

key study

Study period:

Start date of the experimental work: 12 June 2009 and Completion date of the experimental work: 02 July 2009.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Conducted at a GLP accredited laboratory

Justification for type of information:

Experimental techniques are available for the classification of a substance or preparation as oxidising. These are described in EC Test A21. However, Test A21 need not be carried out when examination of the structural formula establishes beyond reasonable doubt that the substance has no oxidising properties. The supplement to the A21 method describes situations in which experimental assessment of oxidising properties is not necessary.

Qualifier:

no guideline followed

Principles of method if other than guideline:

Exemption statement

GLP compliance:

no

Key result

Parameter:

other: Expert statement

Remarks on result:

not measured/tested

Remarks:

The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Assessment of Oxidising Properties of 4,4'-Methylenediphenyl diisocyanate, oligomers

Examination of the structural formula indicates:

• The molecule does not contain any functional groups listed in Table 17.3. Although this list is not exhaustive, this is a significant observation as most commonly occurring oxidising functional groups are contained within the list.

• According to the two criteria quoted, oxidising properties can exist when:

o the electronegative atoms which are present constitute a high proportion of the molecule and are bound to elements in a high oxidation state In the case of 4,4'-Methylenediphenyl diisocyanate, oligomerst he proportion of electronegative atoms in the molecule is low. In addition, none of the oxygen atoms are bound to elements of a high oxidation state. All of the oxygen atoms are bound to carbon.

o the electronegative atoms are bonded to each other or to other electronegative elements such as iodine, nitrogen, sulphur or phosphorus. In the case of the test substance the electronegative atoms are not bound to one another, nor to any other electronegative elements.

o Assessment against these two criteria indicates strongly that the molecule will not have oxidising properties.

In every respect of the oxidising properties exemption procedure, the test substance does not show any evidence of possessing oxidising properties.

On the basis of this exercise, the material should be considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Interpretation of results:

GHS criteria not met

Conclusions:

The test item is considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Description of key information

The test item is considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Key value for chemical safety assessment

Oxidising properties:

non oxidising