Registration Dossier
Registration Dossier
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EC number: 201-557-4 | CAS number: 84-74-2
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: taken from RAR
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
- Objective of study:
- absorption
- distribution
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- taken fom EU RAR
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Dibutyl phthalate
- EC Number:
- 201-557-4
- EC Name:
- Dibutyl phthalate
- Cas Number:
- 84-74-2
- Molecular formula:
- C16H22O4
- IUPAC Name:
- dibutyl phthalate
Constituent 1
- Radiolabelling:
- yes
- Remarks:
- 14C-DBP
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Main ADME results
- Type:
- absorption
- Results:
- readily absorbed
Toxicokinetic / pharmacokinetic studies
Toxicokinetic parameters
- Test no.:
- #1
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): low bioaccumulation potential based on study results
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