Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The skin senzitisation potential of strontium ferrite was assessed in a test according to OECD 406 and UN-GHS. 20 animals (guinea pigs) were used for testing strontium ferrite, 10 animals 10 were in the negative and positive control group. The positive control group was exposed to undiluted HCA =α-Hexylcinnamaldehyde.

Observation of skin reactions was conducted at 24 and 48 hours after removal of the challenge patch. The skin reactions were recorded according to the grades shown in Magnusson and Kligman Grading Scale as follows:

Skin reaction

Grades

No visible change

Discrete or patchy erythema

Moderate and confluent erythema

Intense erythema and swelling

0

1

2

3

The average Magnusson and Kligman grade of animals in the negative control group is 0 (i.e. <1) during 24 and 48 hrs observations.

The percentage of animals shown Magnusson and Kligman grades of 1 or greater in test group is 0% (i.e. <15%) during 24 and 48 hrs observations.

The percentage of animals shown Magnusson and Kligman grades of 1 or greater in positive control group is 100% (i.e. >15%) during 24 and 48 hrs observations.    

Based on the above results, strontium ferrite (“Manipermpulver”) did not produce skin sensitization in guinea pigs.

Strontium ferrite is to be considered as non-sensitizing to the skin. Classification is not required.


Migrated from Short description of key information:
Strontium ferrite does not cause skin sensitisation.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

From experience strontium ferrite is not sensitising via the respiratory route. Studies on this endpoint are not available.


Migrated from Short description of key information:
From experience strontium ferrite is not sensitising via the respiratory route.

Justification for classification or non-classification

Strontium ferrite is to be considered as non-sensitizing to the skin. Thus classification is not required.