Registration Dossier
Registration Dossier
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EC number: 215-693-7 | CAS number: 1344-37-2 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77603.
Endpoint summary
Administrative data
Description of key information
Two acute oral studies are available (BASF AG, Report No XXIV/62, 08 Oct 1974; BASF AG, Report No XXIV/61, 08 Oct 1974) all comparable to OECD guideline 401 but were conducted prior to the existence of guidelines. The LD50 was determined in the 2 studies to be higher than 10000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via dermal route
Endpoint conclusion
- Value:
- mg/kg bw
Additional information
In the 2 available studies, rat (Sprague-Dawley; 5 animals per sex) were treated (gavage) with test substance suspended in 0.5% aqueous CMC (concentration of test substance in vehicle: 35%). Daily check for mortality and clinical signs were performed up to 14 days after treatment, as well as pathological analysis of death and survivors animals at necropsy.
No mortality, clinical signs or abnormalities were observed at dose levels up to 10000 mg/kg bw with rats. The urine and feces were discolored during the first days post substance application. The LD50 was determined to be in excess of 10000 mg/kg bw in rats.
The acute dermal and inhalation toxicity was not tested.
Justification for classification or non-classification
Because the LD50 exceeds the classification limit of 5,000 mg/kg bw (GHS) and 2,000 mg/kg bw (67/548/EEC), a classification is not warranted.
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