Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Adequacy of study:
other information

Data source

Reference
Title:
No information
Author:
Bernhard, A.M. et al. Toxicol. Lett. 45, 271-280 (1989)

Materials and methods

Principles of method if other than guideline:
Method: other: 5 rats/group, collection of 24 h urine after last injection, determination of urinariy concentration of albumin and beta-2-microglobulin
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
IUCLID4 Test substance: other TS: cyclopentane, analytical grade giveb in cornoil

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
female

Administration / exposure

Route of administration:
intraperitoneal
Duration of treatment / exposure:
2 weeks
Frequency of treatment:
5 times/week
Doses / concentrations
Remarks:
Doses / Concentrations:
1 500 mg/d
Control animals:
yes, concurrent vehicle
Details on study design:
Post-exposure period: no data

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion