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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

Based upon the results of a flow through fresh water test (MITI 1992) conducted over 8 weeks with Cyprinus carpio at two nominal concentration levels, 2 µg/l (135-360 L/kg) and 20 µg/l (128-436 L/kg), it can be concluded that 2,4-di-tert-butylphenol has a moderate bioaccumulation potential.
Using the BCFWIN (v3.0) model with a measured Log Kow value of 4.8, the BCF fish is predicted to be 409 L/kg wwt for 2,4-DTBP. This predicted BCF fish is consistent with the experimental values obtained in the MITI study and therefore the worst case experimental value of 436 L/kg in fish will be used in the risk assessment. 
The TGD calculations have been shown to be very conservative, estimating a BCF for fish of 2400 L/kg wwt. However, as there are no experimental data available for BCF in earthworms, the TGD calculated BCF earthworm of 758 L/kg wwt, will be used in the risk assessment.

Key value for chemical safety assessment

BCF (aquatic species):
436 L/kg ww

Additional information