4-[(2,5-dichlorophenyl)azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide

Nanomaterial dustiness

Administrative data

Endpoint:

nanomaterial dustiness

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10.12.2020 - 13.01.2021

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Remarks:

according to DIN EN 17199-3

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2021

Report date:

2021

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: EN 17199-3

Version / remarks:

measurement of dustiness of bulk materials that contain or release respirable NOAA or other
respirable particles - Part 3: Continuous drop method

GLP compliance:

no

Type of method:

continuous drop

Sampling:

The product was used without special pre-treatment, such as drying or similar.

Test material

Test material information

Constituent 1

Reference substance name:

4-[(2,5-dichlorophenyl)azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide

EC Number:

227-930-1

EC Name:

4-[(2,5-dichlorophenyl)azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide

Cas Number:

6041-94-7

Molecular formula:

C23H15Cl2N3O2

IUPAC Name:

4-[(2,5-dichlorophenyl)diazenyl]-3-hydroxy-N-phenyl-2-naphthamide

Test material form:

solid: nanoform, no surface treatment

Results and discussion

Dustiness index

Dustiness index 1

Key result

Mean:

106 875.8 other: 1/mg

St. dev.:

0 other: not relevant

Remarks on result:

other:

Remarks:

dustiness index as number of airborne particles per mg in the nanoscale (10 nm - 100 nm)

Dustiness index 2

Mean:

9 034 other: N/cm3

St. dev.:

0 other: not relevant

Remarks on result:

other: number of airborne nanoparticles per cm3

Any other information on results incl. tables

Measurement duration: 10 min

temperature: 14°C, rel. air humidity 43%

table 1: summary SMPS (sanning mobility particle sizer)

Range [nm]  Mean [nm]  Concentration [N/cm³] ICD [1/mg]   ECD [1/mg·s]  10-100 42,1 9034,0 106875,8 178,1  100-417 152,9 1219,2 14423,7 24,0  10-417 55,3 10253,2 121299,5 202,2

ICD: dustiness index as number of airborne particles per mg

ECD: emission rate as number of particles per mg per second

mean: average particle diameter in nm

N: number of airborne particles

table 2: summary OPS (optical particle sizer)

Range [µm]  Mean [µm]  Concentration [N/ cm3] ICD[1/mg]   ECD[1/mg x s]  0.3 - 10 6,0  74,0 876,0 1,5

Applicant's summary and conclusion

Executive summary:

The dusting behaviour of the test material was investigated using DIN EN 17199 -3: 2019 -12 "workplace exposure - measurement of dustiness of bulk materials that contain or release respirable nano objects and their aggregates and agglomerates or other respirable particles- Part 3: Continuous drop method".

The dust released by the falling test material was measured by a scanning mobility particle sizer (SMPS,10 - 417 nm) and an optical particle sizer (3 - 10 µm). The counterflow was provided by cleaned, almost particle-free air.

The SMPS counted 9034.0 particles per cm3 in the nanoscale 10 - 100 nm. corresponding to a dustiness index of 106875.8 particles per mg in the nanoscale 10 - 100 nm. The mean size of the nanoparticles in the range 10 -100 nm was 42.1.

The OPS (0.3 - 10 µm) counted 74.0 particles per cm3 corresponding to a dustiness index of 876.0 particles per mg. The mean size of the particles was 6.0 µm.