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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes (incl. QA statement)
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Reference substance name:
Acetic acid, oxo-, sodium salt, reaction products with ethylenediamine and phenol, iron sodium salts
EC Number:
283-044-5
EC Name:
Acetic acid, oxo-, sodium salt, reaction products with ethylenediamine and phenol, iron sodium salts
Cas Number:
84539-55-9
Molecular formula:
non specified (UVCB substance)
IUPAC Name:
Acetic acid, oxo-, sodium salt, reaction products with ethylenediamine and phenol, iron sodium salts
Details on test material:
- Lot/batch No.: FRH 5271 AG
- Storage condition of test material: room temperature in the dark
- Analytical purity: 100 % (UVCB)

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
unchanged (no vehicle)
Duration of exposure:
24 hour
Doses:
2000 mg/kg bodyweight
No. of animals per sex per dose:
5
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Mortality:
No deaths
Clinical signs:
other: No signs of systemic toxicity
Gross pathology:
No abnormalities
Other findings:
Signs of skin irritation: slight to well defined erythema, very slight to slight oedema

Applicant's summary and conclusion

Conclusions:
The acute dermal LD50 was found to be greater than 2000 mg/kg bodyweight.