(3-chloro-2-hydroxypropyl)trimethylammonium chloride

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption

Remarks:

adsorption

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2005-06-15 to 2006-10-28

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study was conducted in accordance with generally accepted scientific principles and in compliance with GLP.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: OECD 303A

Principles of method if other than guideline:

The adsorption coefficient was determined by analytical measurment of test substance concentrations in water and sludge on six test days during the course of an OECD 303A simulation study.

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Adsorption to sludge measured during OECD 303A simulation study

Media:

sewage sludge

Test material

Test material information

Constituent 1

Reference substance name:

(3-chloro-2-hydroxypropyl)trimethylammonium chloride

EC Number:

222-048-3

EC Name:

(3-chloro-2-hydroxypropyl)trimethylammonium chloride

Cas Number:

3327-22-8

Molecular formula:

C6H15ClNO.Cl

IUPAC Name:

3-chloro-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride

Details on test material:

- Name of test material (as cited in study report): (3-chloro-2-hydroxypropyl)trimethylammonium chloride

- Physical state: Liquid (aqueous solution)

- Analytical purity: 65.3% active ingredient

- Impurities (identity and concentrations): <1% EPTAC; <10% DHPTAC

- Purity test date: 2005-03-23

- Lot/batch No.: 153768

- Expiration date of the lot/batch: March 2006

- Storage condition of test material: Room temperature, protected from moisture and light

Radiolabelling:

no

Study design

Test temperature:

20±2 °C

Batch equilibrium or other method

Analytical monitoring:

yes

Details on sampling:

Samples of water and sludge were taken for analysis on days 57, 61, 64, 111, 112 and 113 of the test.

Details on matrix:

Test matrix was sewage effluent and sludge from an OECD 303A simulation study.

Computational methods:

Kpsludge = conc. in sludge/conc. in water

Although the organic carbon content of the sludge was not measured during the test, it has been assumed that the proportion of the organic carbon in sludge is 50 %.

Koc =

Results and discussion

Adsorption coefficient

Type:

Koc

Value:

68.8

Applicant's summary and conclusion

Validity criteria fulfilled:

not applicable

Conclusions:

As part of an OECD 303A degradation simulation study, measured concentrations of CHPTAC in sludge and water were used to determine the Koc based on an assumed organic carbon content of 50%. The measured Kp sludge was 34.4 kg/l, equivalent to Koc = 68.8 kg/l.