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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

An acute daphnid toxicity study was conducted in accordance with OECD Guideline 202 on tripropenyl succinic acid (CAS RN 147384-84-7), by read-across based on a grouping of substances (category approach). 

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

An acute daphnid toxicity study was conducted in accordance with OECD Guideline 202 on tripropenyl succinic acid (CAS RN 147384-84-7), by read-across based on a grouping of substances (category approach). The test was conducted under static conditions as a limit test at 100 mg/L. The NOEC was reported at 100 mg/L, and the EC50was reported as ˃ 100 mg/L.

A category approach is used for the hazard assessment of several endpoints. The hypothesis for the category of C8-12 Alkenyl Succinic Anhydrides is that data can be read-across among members of the category, because the properties and behaviours of category members are similar, based on common functional groups, similar breakdown products, and demonstration of a constant pattern associating the potency of properties with the various carbon chain lengths. Functional groups include a dihydro-2,5-furandione cyclic anhydride ring, a carbon chain of length 8 -12 carbons, and a single carbon-carbon double-bond within the carbon chain. The primary functional group associated with toxicity is the succinic anhydride moiety, which is quickly hydrolysed to form a butanedioic acid. A constant pattern may also be displayed in acute toxicity, dermal irritancy and biodegradation, with the lowest carbon chain length (C8) displaying the highest activity. Irritation, toxicity and degradation potential diminish with increasing carbon chain length. Read-across among the category members is substantiated by the common behaviour in physico-chemical and toxicity behaviours, as provided in the Chemical Category Report Format (CCRF) attached to the IUCLID file. It is adequate to fulfil the information requirements of Annex IX, to be the basis for classification and labelling decisions, and for risk assessment.