Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

A Guinea Pig Maximization Test (GPMT) according to OECD TG 406 and GLP was performed on female guinea pigs. The study was conducted with the following test item concentrations: intradermal induction: 5%; topical induction: 50%; challenge: 12%. The challenge led to no skin effects in the treated animals or in the control group (H.W. Vohr 2000).

Migrated from Short description of key information:
TMQ was not sensitizing in a guinea pig maximization test (GPMT) conducted according to OECD TG 406. There are no reliable human studies available.

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
There are no data available.

Justification for classification or non-classification

Based on the available information no classification is required according to the EU classification criteria 67/548/EWG and regulation no. 1272/2008 (GHS).