Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.031 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.036 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.003 mg/L
Assessment factor:
100

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
912 mg/L
Assessment factor:
1
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
1.67 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.167 ng/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.314 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Studies on aquatic organisms are available for member of the fatty acid category. For the fatty acid mixture, C12 -18, no studies are available. Thus, read-across is performed to studies conducted with the pure homologues which are contained (> 10%) in the mixture. Lauric acid (C12 - CAS 143 -07 -7) is the most acute toxic and myristic acid (C14 - CAS 544 -63 -8) the most chronic toxic homologue of the mixture. PNEC (freshwater and marine)-calculations are based on LC50/NOEC-values available for these constituents. In case of PNECstp the EC10 of a microorganism study conducted with octanoic acid (C8) is used. PNECsediment and PNECsoil are based on equilibrium partitioning method on the basis of freshwater and marine PNEC-values. Due to the low potential for bioaccumulation, PNECoral is not determined.

Conclusion on classification

Daphnids were found to be the most sensitive aquatic species in acute tests conducted with lauric acid (C12 - CAS 143 -07 -7). The EC50 (72 h) is determined to be 3.6 mg/L and the substance is readily biodegradable. Thus CAS 67701-01 -3 is not classified according to the Directive 67/548/EEC and the GHS Regulation (EC) No. 1272/2008.