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EC number: 202-859-9 | CAS number: 100-51-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: reporting suffers from deficiencies
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- The classification of Skin irritants by human patch test
- Author:
- Basketer DA, Chamberlain M, Griffiths HA, Rowson M, Shittle E, York M
- Year:
- 1 997
- Bibliographic source:
- Food Chem Toxicol 35, 845-852
- Reference Type:
- publication
- Title:
- Determination of skin irritation potential in the human 4-h patch test
- Author:
- Basketer DA, York M, McFadden JP, Robinson MK
- Year:
- 2 004
- Bibliographic source:
- Contact Dermatitis 51, 1-4
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- patch test in humans
- GLP compliance:
- no
Test material
- Reference substance name:
- Benzyl alcohol
- EC Number:
- 202-859-9
- EC Name:
- Benzyl alcohol
- Cas Number:
- 100-51-6
- Molecular formula:
- C7H8O
- IUPAC Name:
- phenylmethanol
- Details on test material:
- no further data
Constituent 1
Method
- Type of population:
- general
- Subjects:
- volunteers
- Ethical approval:
- not specified
- Route of exposure:
- dermal
- Reason of exposure:
- intentional
- Exposure assessment:
- measured
- Details on exposure:
- patch test in human
- Examinations:
- skin irritancy
- Medical treatment:
- no data
Results and discussion
- Clinical signs:
- 1/31 weekly positive reaction usually characterized by mild erythema or dryness across most of the treatment site)
compared to 17/32 in the positive control group - Results of examinations:
- weekly positive reaction(usually characterized by mild erythema or dryness across most of the treatment site) was observed in 1/31 volunteers compared to 17/32 in the positive control group. Therefore it was concluded that there is no need to classify
- Effectivity of medical treatment:
- no data
- Outcome of incidence:
- 1/31 (mild erythema) vs 17/32 in the positive control group
Any other information on results incl. tables
weekly positive reaction(usually characterized by mild erythema or dryness across most of the treatment site) was observed in 1/31 volunteers compared to 17/32 in the positive control group Therefore it was concluded that there is no need to classify
Applicant's summary and conclusion
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