Registration Dossier
Registration Dossier
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EC number: 207-938-1 | CAS number: 502-44-3
Endpoint summary
Administrative data
Description of key information
The half-life for hydrolysis of e-Caprolactone (Capa monomer) in sterile aqueous solution (at a concentration of ca 1 g/L) was 15.7, 52.5 and 2.2 days at pH values of 4, 7 and 9, respectively (OECD 111). At all pH values the hydrolysis product was 6-hydroxyhexanoic acid which was stable to any further hydrolysis.
The test substance can be classified as readily biodegradable.
Requirements for bioaccumulation testing and adsorption/desorption testing were waived as the log Pow value of e-caprolactone (Capa monomer) is 0.32 (see section 4.7, partition coefficient).
Additional information
According to column 2 of Annex IX of the REACH Regulation, no bioaccumulation study is required if the log Pow is below the trigger of 3 as the substance can be expected to have a low potential for bioaccumulation. Furthermore, simulation testing in water and/or sediment and in soil does not need to be conducted as the substance is readily biodegradable.
According to column 2 of Annex VIII of the REACH regulation, no adsorption/desorption study is required if the log Pow is below the trigger of 3 as the substance can be expected to have a low potential for adsorption. Based on the log Pow value of 0.32 (OECD 117), the substance can be expected to have a low potential for adsorption.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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