Registration Dossier
Registration Dossier
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EC number: 500-114-5 | CAS number: 52408-84-1 1 - 6.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term aquatic toxicity:
Reliable short-term toxicity tests for the registered substance are available for fish, algae and for daphnia.
In the fish study, Danio rerio were exposed for 96h in a static system. The LC50 was 5.74 mg/L (PARAD consortium, NOACK, 2010, D. Scheerbaum).
In the one available acute daphnia study, Daphnia magna were exposed for 48h in a static system. The LC50 is 91.4 mg/L (PARAD consortium, NOACK, 2010, D. Scheerbaum).
In the one available algae study, the 72h-LC50 for growth rate is 12.2 mg/L (PARAD consortium, NOACK, 2010, D. Scheerbaum).
Long-term aquatic toxicity:
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity to aquatic organisms shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms.
The results of the risk assessment covering all relevant exposures throughout the life cycle of the submission item demonstrate the absence of a risk to the environment. The environmental concentrations were predicted and compared to the respective PNECs. The resulting RCRs for all identified uses were clearly below 1. Consequently, a need to investigate further the effects on aquatic organisms is not indicated.
Toxicity to microorganisms:
A reliable study assessing the toxicity of the registered substance to microorganisms (OECD 209) is available. Based on the respiration rate, the EC20 was determined to be 507mg/l whereas the EC50 is > 1000 mg/l (PARAD consortium, NOACK, 2010, S. Fiebig).
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