Pin-2(3)-ene

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

September 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Well documented study performed according to OECD 103 guideline and EU method A.2, under GLP and without deviation

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Boiling pt.:

ca. 154.3 °C

Atm. press.:

ca. 1 010 hPa

Decomposition:

no

Remarks on result:

other: First determination

Boiling pt.:

ca. 154.4 °C

Atm. press.:

ca. 1 019.2 hPa

Decomposition:

no

Remarks on result:

other: Second determination

Key result

Boiling pt.:

ca. 154.3 °C

Atm. press.:

ca. 101.3 kPa

Remarks on result:

other: Corrected value with the Sydney Young equation

Pre-study:

Peaks assigned to the boiling of the substance were observed and measurement was stopped at 250°C (Figure 1).Temperatures corresponding to these peaks were used to create the following temperature program:

Temperature program:

Step	Initial temperature (°C)	Final Temperature (°C)	Heating rate (°C/min)	Duration (min)	Furnace atmosphere	Rate* (mL/min)	Liquid nitrogen cooling
1	20	-120	10	14	He	60	YES
2	-120	-120	0	5	He	60	NO
3	-120	210	10	40	He	60	NO

*Gas injection rate in the furnace. 

 

First Determination:

 

Mass taken: 11.73 mg

 

Results

Initial boiling point is observed at 154.3°C (onset temperature of the first peak) and a corresponding mass loss is observed on the TG curve, showing that all the substance was evaporated at the end of the study.

The crucible was visually checked after the determination: by opening the crucible, no test item left in the crucible and no sign of decomposition was observed.

Atmospheric pressure: 1010.0 hPa

Second Determination:

 

Mass taken: 11.36 mg

Results :

Initial boiling point is observed at 154.4°C (onset temperature of the first peak) and a corresponding mass loss is observed on the TG curve, showing that all the substance was evaporated at the end of the study. 

The crucible was visually checked after the determination: by opening the crucible, no test item left in the crucible and no sign of decomposition was observed.

Atmospheric pressure: 1019.2 hPa

Conclusions:

According to guideline OECD 103 and method EU A.2, the initial boiling point of substance alpha-pinene multiconstituent was determined as 154.3°C at 101.3 kPa after correction using the Sydney Young equation.

Executive summary:

A study was performed to determine the boiling point of test item alpha-pinene multiconstituent. The method used was Differential Scanning Calorimetry (DSC) and the test was conducted according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103, "Boiling Point" (1995)

In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. Heat flow differences between the two crucibles and mass variation were recorded on a thermogram.

Two trials were conducted and corresponding thermograms were obtained, giving us the following results:

Trial	Initial boiling point	Ambient pressure
1	154.3°C	1010.0 hPa
2	154.4°C	1019.2 hPa

The initial boiling point value respect validity criteria (less than 0.5°C up to 326.85°C (600K) and less than 2°C up to 1000°C (1273 K)).

After correction using the Sydney Young equation, the initial boiling point of the substance was determined as 154.3°C at 101.3 kPa.

Reference 2

Endpoint:

boiling point

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

α-Pinene is a bicyclic monounsaturated monoterpene and (-)-α-pinene is an enantiomeric form of α-pinene. Therefore, data on (-)-alpha pinene can be extrapolated to alpha-pinene. (see read-across justification document in section 13).

Reason / purpose for cross-reference:

read-across source

Boiling pt.:

ca. 155.5 °C

Atm. press.:

ca. 1 018.3 hPa

Decomposition:

no

Remarks on result:

other: First determination

Boiling pt.:

ca. 155.2 °C

Atm. press.:

ca. 1 025.5 hPa

Decomposition:

no

Remarks on result:

other: Second determination

Boiling pt.:

ca. 155 °C

Atm. press.:

ca. 101.3 kPa

Remarks on result:

other: Corrected value with the Sydney Young equation

Pre-study:

Peaks assigned to the boiling of the substance were observed and measurement was stopped at 550°C (Figure 1).Temperatures corresponding to these peaks were used to create the following temperature program:

Temperature program:

Step	Initial temperature (°C)	Final Temperature (°C)	Heating rate (°C/min)	Duration (min)	Furnace atmosphere	Rate* (mL/min)	Liquid nitrogen cooling
1	20	-120	10	14	He	60	YES
2	-120	-120	0	5	He	60	NO
3	-120	210	10	40	He	60	NO

*Gas injection rate in the furnace. 

 

First Determination:

 

Mass taken: 11.01 mg

 

Results

Initial boiling point is observed at 155.5°C (onset temperature of the first peak) and a corresponding mass loss is observed on the TG curve, showing that all the substance was evaporated at the end of the study.

The crucible was visually checked after the determination: By opening the crucible, no test item left in the crucible and no sign of decomposition was observed.

Atmospheric pressure: 1018.3 hPa

Second Determination:

 

Mass taken: 13.32 mg

 

Results :

Initial boiling point is observed at 155.2°C(onset temperature of the first peak) and a corresponding mass loss is observed on the TG curve, showing that all the substance was evaporated at the end of the study. 

The crucible was visually checked after the determination: By opening the crucible, no test item left in the crucible and no sign of decomposition was observed.

Atmospheric pressure: 1025.5 hPa

Conclusions:

According to OECD 103 guideline and EU method A.2, the initial boiling point of substance (-)-alpha-pinene was determined as 155.0°C at 101.3 kPa after correction using the Sydney Young equation.

Executive summary:

A study was performed to determine the boiling point of test item (-)-alpha-pinene. The method used was Differential Scanning Calorimetry (DSC) and the test was according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103, "Boiling Point" (1995)

In this method, two crucibles were put in the apparatus furnace under inert atmosphere (helium) at atmospheric pressure. One crucible contained the test item, the other was empty and considered as the reference. A specific temperature program was applied. Heat flow differences between the two crucibles and mass variation were recorded on a thermogram.

Two trials were conducted and corresponding thermograms were obtained, giving us the following results:

Trial	Initial boiling point	Ambient pressure
1	155.5°C	1018.3 hPa
2	155.2°C	1025.5 hPa

This study respects validity criteria (the difference temperature between the two determinations is less than 1°C), therefore it is considered valid.

After correction using the Sydney Young equation, the initial boiling point of the substance was determined as 155.0°C at 101.3 kPa.

Description of key information

The boiling point of alpha-pinene multiconstituent was determined to be 154.3°C at 101.3 kPa.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

154.3 °C

Additional information

Key study conducted according to the OECD 103 Guideline and the EU A.2 method, under GLP without deviation and with certificate of analysis included. Therefore, a reliability of 1 is assigned and the result of this key study is proposed as the end point value.

This result is supported by consistent experimental data obtained with (-)-alpha-pinene.