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EC number: 932-231-6
CAS number: 1335202-81-7
data: The litter parameters assessed included litter size, fetal loss
and litter weight. These
parameters were not significantly affected by any dosage. Mean
pup weights were statistically higher at 0.2, 2.0 and 300 mg/kg.
Female rats were given LAS orally in distilled water from gestation days
6 to 15 during pregnancy. Some effects such as decreased weight gain and
transient diarrhea occurred at the highest dose. Pregnancy rates were
comparable at all doses. Litter parameters were not significantly
affected at any dose. No significant differences were observed in
visceral anomalies or skeletal variants, with the exception of a
marginal retardation of sternabral ossification at the highest dose.
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