Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Two producers of trimethoxy(methyl)silane have provided statements which confirm that there have been no cases of skin sensitisation amongst workers during more than 20 years of manufacture (Wacker, 2017; Momentive, 2017).

These data included internal information from: relevant plants, number of employees, exposure description; medical surveillance, regular health checks (especially concerning skin status) already performed on employees of the relevant plants, information from the Network of Departments of Dermatology for the surveillance and scientific evaluation of contact allergies, information from Employer's liability insurance association (BG Bau), information from customer and a comprehensive literature search there have been no cases of skin sensitisation during more than 20 years of production, handling and use of trimethoxy(methyl)silane.

There is therefore no evidence that this substance causes skin sensitisation under relevant exposures in workers.

Additional information