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EC number: 293-208-8 | CAS number: 91052-47-0
No toxic effects up to the limit of water solubility (< 1 mg/L) for Daphnia magna (OECD 202), read-across.
No studies investigating the short-term toxicity of Glycerides, C16-18 mono- (CAS No. 91052-47-0) to aquatic invertebrates are available. Therefore, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related category members Glycerides, C16-18 and C18-unsatd. (CAS No. 67701-30-8) was conducted. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance within this category was used.
One study evaluating the acute toxicity of Glycerides, C16-18 and C18-unsatd. to aquatic invertebrates is available (Küch, 1995). This limit test was conducted according to EU-Method C.2, under GLP conditions. The test was performed with additional consideration of the VCI concept for poorly soluble substances. Thus, two different test solutions were prepared with 100 mg/L: One solution where the test substance was directly weighed into the test vessel and undissolved substance was not removed and a second solution with separation of undissolved substance through filtration. Furthermore no effects were observed in an oversaturated solution with undissolved test substance.
Based on the results obtained for the structurally related analogue (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), no acute toxicity of Glycerides, C16-18 mono- (CAS no. 91052-47-0) to aquatic invertebrates up to the limit of its water solubility is expected.
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