Registration Dossier
Registration Dossier
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EC number: 216-971-0 | CAS number: 1709-70-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Read across to structural analogue substance CAS No. 27676 -62 -6. Justification attached.
20 guinea pigs were induced with the test substance by intradermal injections and dermal applications according to OECD guideline no. 406. 10 control animals were induced with the vehicle only. Both groups were challenged with the test article by dermal application, and the skin reactions were evaluated 24 and 48 hours after removing of the challenge dressing. Under the experimental conditions employed, 0% of the animals of the test group showed skin reactions 24 and 48 hours after removing the dressings. The test substance is therefore regarded as not sensitizing.
Migrated from Short description of key information:
Result determined using OECD test guideline 406.
Not sensitising
Justification for selection of skin sensitisation endpoint:
Result determined using OECD test guideline 406
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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