Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Read across to structural analogue substance CAS No. 27676 -62 -6. Justification attached.

20 guinea pigs were induced with the test substance by intradermal injections and dermal applications according to OECD guideline no. 406. 10 control animals were induced with the vehicle only. Both groups were challenged with the test article by dermal application, and the skin reactions were evaluated 24 and 48 hours after removing of the challenge dressing. Under the experimental conditions employed, 0% of the animals of the test group showed skin reactions 24 and 48 hours after removing the dressings. The test substance is therefore regarded as not sensitizing.


Migrated from Short description of key information:
Result determined using OECD test guideline 406.
Not sensitising

Justification for selection of skin sensitisation endpoint:
Result determined using OECD test guideline 406

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification