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Toxicity to microorganisms

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Description of key information

A 3-h EC50 value of >67 mg/L is observed in activated sludge based on respiration inhibition, which corresponds to a 3-h EC50 value of >36 mg/L based on fluoride. The 3-h EC50 value of >36 mg fluoride/L is used in the assessment.

Key value for chemical safety assessment

EC50 for microorganisms:
36 mg/L

Additional information

No toxicity test with microorganisms is available for potassium tetrafluoroaluminate. The results from the structural analogue multiconstituent aluminium potassium fluoride are used instead (for details see Reporting Format as attached to the respective IUCLID entry and CSR Appendix B.3). One GLP-compliant OECD 209 guideline study is available for the toxicity to microorganisms. The 3-h EC50 is >75 mg/L in activated sludge (Solvay Pharmaceuticals, 2010c). As the contents of fluoride, expressed as a percentage of the molar weight in both substances are comparable, namely 53.5% for potassium tetrafluoroaluminate and ca. 51% for multiconstituent aluminium potassium fluoride, as a result no safety factor is applied. Instead, the effect concentrations will be corrected for molecular weight. The corrected effect concentration for potassium tetrafluoroaluminate is >67 mg/L, which corresponds to an effect concentration of >36 mg fluoride/L.