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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

A PNEC is not derived since no adverse effects were observed in long-term tests in the range of the water solubility of the test substances.

Key value for chemical safety assessment

Additional information

For the members of the fatty acid category four chronic tests are available conducted with pure homologues of different chain lengths. The tested homologues were: decanoic acid (C10 - CAS 334-48-5), lauric acid (C12 - CAS 143-07-7), myristic acid (C14 - CAS 544-63-5) and palmitic acid (C16 - CAS 57-10-3). As palmitic acid (C16) is one of the main components of the fatty acid mixture under consideration a read-across is performed to a study conducted for this pure homologue. For stearic acid no chronic test is available.

Fatty acid homologue

NOEC (as reported in the study)

Water solubility*

Test design and species

Reference

C16 - CAS 57-10-3 palmitic acid

0.22 mg/L (measured, twa concentrations)

< 0.05 at 20 °C

21 d, semi-static,Daphnia magna

NITE, 2008

C18 - CAS 57-11-4 stearic acid

--

insoluble

No chronic test available

* see category justification

For the evaluation of chronic effects of palmitic acid (C16: CAS 57 -11 -4) on aquatic invertebrates, daphnids were tested in a limit-test over a period of 21 days (NITE, 2008). The semi-static experiment was conducted according to OECD 211 in compliance with GLP-requirements. The used test concentration of 0.51 mg/L (nominal) corresponding to a mean measured value (time weighted mean) of 0.22 mg/L was above the reported water solubility limit. No effects were observed on daphnids at this test concentration and thus the NOEC is reported to be 0.22 mg/L.

Concluding from the results reported for palmitic acid C16 no chronic risk is expected for the considered mixture.