Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The mutagen assay was scored as the ratio of the number of colonies (total revertants) in the experimental plates over the number of colonies in the control plates (spontaneous revertants). this was taken as the mutagenic ratio. A compounds was considered to be mutagenic if its mutagenic ratio was ≥ 2. The criterion for a strong mutagen was a compound having a mutagenic ratio ≥ 2 at concentration less than 100 µg/plate. A weak mutagen requires greater than 100 µg/plate to produce ratio ≥2.

Short description of key information:
Mutagenesis was measured relative to the known mutagen ethyl methanesulfonate.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification