Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term repeated dose toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
a short-term toxicity study does not need to be conducted because a reliable sub-chronic (90 days) or chronic toxicity study is available, conducted with an appropriate species, dosage, solvent and route of administration
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
In accordance with column 2 of REACH Annex IX, the test repeated dose toxicity after dermal application (required in section 8.6) does not need to be conducted as repeated dose toxicity studies for oral application are available. Sodium cyanate is not irritating and not sensitizing to the skin. No dermal effects are expected for repeated dose application to the skin and a low dermal absorption is expected due to the physico-chemical properties of the substance.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Potassium cyanate
EC Number:
209-676-3
EC Name:
Potassium cyanate
Cas Number:
590-28-3
Molecular formula:
KOCN
IUPAC Name:
potassium cyanate

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion