Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

After intracutaneous injection of styrene oxide to guinea pigs, 6 of 11 animals showed a sensitizing reaction after challenge with styrene oxide. These data indicate that the substance should be classified for skin sensitisation. Therefore, further in-vivo testing for sensitisation is not appropriate according to REACH VO Annex VII, 8.3 Column 2.

Migrated from Short description of key information:
Data indicating a sensitising potential are available.

Justification for classification or non-classification