Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

Currently viewing:

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available

Data source

Reference
Title:
No information
Author:
Plzak V, Doull J (1969). A further survey of compounds for radiation protection. SAM-TR-69-1, NTIS AD691-490, February 1969.

Materials and methods

Principles of method if other than guideline:
Migrated dataset. other: no data
GLP compliance:
no
Remarks:
GLP was not mandatory at the time of the study

Test material

Constituent 1
Chemical structure
Reference substance name:
p-toluidine
EC Number:
203-403-1
EC Name:
p-toluidine
Cas Number:
106-49-0
Molecular formula:
C7H9N
IUPAC Name:
4-methylaniline
Details on test material:
IUCLID4 Test substance: no data

Test animals

Species:
mouse
Sex:
male

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
50 mg/kg bw

Any other information on results incl. tables

Migrated dataset

Applicant's summary and conclusion