Registration Dossier
Registration Dossier
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EC number: 231-588-9 | CAS number: 7646-78-8
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes
Test material
- Reference substance name:
- Tin tetrachloride
- EC Number:
- 231-588-9
- EC Name:
- Tin tetrachloride
- Cas Number:
- 7646-78-8
- Molecular formula:
- Cl4Sn
- IUPAC Name:
- tin tetrachloride
- Details on test material:
- - Name of test material (as cited in study report): Zinntetrachlorid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
Test conditions
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 10 L
- No. of organisms per vessel: 7
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- Biomass loading rate: <= 1g fish / L water
OTHER TEST CONDITIONS
- Adjustment of pH: 8.3
-Temperature: 22+/-1 °C
- Photoperiod: 12h/12h
- Light intensity: ca. 700 Lux
- Water Hardness: 2.1-2.5 mmol CaMg/L
-Oxygen: >= 80% of saturation value
TEST CONCENTRATIONS
0 and 100 mg/L nominal - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- BIOLOGICAL RESULTS
No mortality in the control and the only test concentration of 1000 mg/L. 3 hours after the start of the test all fishes in the test concentration showed different behavior. Symptoms were reversible within the next 3 hours.
ANALYTICAL RESULTS
Concentration < LOD (1.1 mg/L)
Tin tetrachloride precipitated after hydrolysis as Tin(IV)oxide and sedimented
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Tin tetrachloride did not induce acute toxic effects in Brachydanio rerio at a concentration of 1000 mg/L.
- Executive summary:
The effects of Tin tetrachloride on Brachydanio rerio were investigated in an acute fish toxicity test with static desing at a limit dose of 1000 mg/L according to OECD 201 under GLP. The control was valid. Tin tetrachloride did not induce acute toxic effects in Brachydanio rerio at a concentration of 1000 mg/L.
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