Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1953
Report date:
1953
Reference Type:
secondary source
Title:
Unnamed
Report date:
1953

Materials and methods

Principles of method if other than guideline:
BASF-Test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Triisobutyl phosphate
EC Number:
204-798-3
EC Name:
Triisobutyl phosphate
Cas Number:
126-71-6
Molecular formula:
C12H27O4P
IUPAC Name:
triisobutyl phosphate

Test animals

Species:
other: mammal
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Duration of treatment / exposure:
4 Tage
Frequency of treatment:
6 h/Tag
Doses / concentrations
Remarks:
gesaettigte Atmosphaere (Zimmertemperatur) entspr. 0,3-1 mg/l
Control animals:
other: no data specified
Details on study design:
Post-exposure period: keine Angabe

Results and discussion

Results of examinations

Details on results:
1 Maus unter Dyspnoe gestorben, sonst symptomlos vertragen.

Effect levels

Dose descriptor:
NOAEC
Remarks on result:
other: not determined

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion