Registration Dossier
Registration Dossier
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EC number: 701-374-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Data show slight irritation to the skin and eye, which is fully reversible and below the level of classification.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
The material appears to be a mild primary skin irritant (mean erythema score of 1 at 24 hrs and 0.6 48 hrs) when tested as a 10% w/v suspension in mineral spirits. It does not appear to be a fatiguing agent or a sensitizing agent in the albino guinea pig. The effects are reversible and below the level of classification as a skin irritant.
Treatment of the eyes with the neat substance resulted in average ocular irritation scores of 3.3, 2.3, 0.7, 0.0, and 0.0 on days 1, 2, 3, 5 and 7, respectively. The eye irritant was reversible and below the level of classification as an eye irritant.
Justification for classification or non-classification
Slight skin and eye irritant, though irritation scores are well below the level of classification.
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