Registration Dossier

Administrative data

Description of key information

The test substance, 2,3-epoxypropyl o-tolyl ether was evaluated for eye and skin irritating potential in O.E.C.D. test guideline 404 and 405 studies wiht GLP compliance.  

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

The test substance was not irritating to the rabbit eye or skin when tested by O.E.C.D. test guideline methods. The Primary Irritation Index (PII) for rabbit skin was 1.2 suggesting that the test substance is a mild irritant.

Justification for classification or non-classification

The data from standard O.E.C.D. test guideline studies demonstrates that the test substance is not irritating. No Classification and Labeling for irritation is required.