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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Study initiation date: 13 October 2009 Study completion date: 14 July 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Key result
Type:
Pow
Partition coefficient:
32
Temp.:
25 °C
Remarks on result:
other: pH value not specified - substance not ionisable, pH not relevant for result
Type:
log Pow
Partition coefficient:
1.5
Temp.:
25 °C
Remarks on result:
other: pH value not specified - substance not ionisable, pH not relevant for result
Conclusions:
Partition coefficient n-octanol / water (OECD 117): Pow = 32; log Pow = 1.5 (25 °C)
Executive summary:

The partition coefficient n-octanoll water (Pow) of the test item was determined according to OECD

guideline no. 117 [adopted on 13 April 2004] and EU test method A.8 [Directive 92/69/EEC, Official

Journal L 383 A 1992] with the HPLC method.

The test item consists of different components with different log Pow-values:

Partition coefficient n-octanol / water (POW):     POW= 32  log POW= 1.5

The test(s) used to generate this report was(were) carried out in compliance with the principles of Good Laboratory Practice (GLP) in accordance with the currently valid German Chemical Substance Act (Chemikaliengesetz – ChemG), the underlying Commission Directive 2004/10/EC of 11 February 2004 and the relevant OECD decision of the council on 26 November 1997 and that the results fully reflect those found in the study.

Description of key information

Partition coefficient n-octanol / water (OECD 117): Pow =  32;  log Pow = 1.5 (25 °C)

Key value for chemical safety assessment

Log Kow (Log Pow):
1.5
at the temperature of:
25 °C

Additional information