Registration Dossier

Administrative data

Endpoint:
dermal absorption in vivo
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study meets generally accepted scientific principles For read-across justification refer to section 13.

Data source

Reference
Reference Type:
publication
Title:
The Metabolism of 14C Labeled Ethylenediaminetetraacetic Acid in Human Beings
Author:
Foreman, H. et al
Year:
1954
Bibliographic source:
J. Lab. and Clin. Med.43; 566-571

Materials and methods

Principles of method if other than guideline:
Details on study design: - 3 young healthy adult male were used in each application group
Endpoint addressed: basic toxicokinetics
Endpoint addressed: dermal absorption

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- no further data available

Results and discussion

Applicant's summary and conclusion

Conclusions:
CaNa2EDTA does not penetrate the skin.