Trisodium 2-(carboxylatomethyl(2-hydroxyethyl)amino)ethyliminodi(acetate)

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

June 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: NEN-ISO 13320, Particle Size analysis - laser diffraction methods, October 2009

Deviations:

no

GLP compliance:

no

Remarks:

according to Internal Management System

Type of method:

Laser scattering/diffraction

Type of distribution:

other: laser diffraction

Key result

Percentile:

D50

Mean:

240 µm

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

Key result

Percentile:

D10

Mean:

105 µm

St. dev.:

2

Remarks on result:

other: RSD 1.8%

Key result

Percentile:

D50

Mean:

240 µm

St. dev.:

6

Remarks on result:

other: RSD 2.4%

Key result

Percentile:

D90

Mean:

410 µm

St. dev.:

22

Remarks on result:

other: RSD 5.4%

Table 6.1: PSD characteristics of Hydroxyethylethylenediaminetriacetic acid, trisodium salt

Sample replicate	d10	d50	d90
	[μm]	[μm]	[μm]
1	104	237	404
2	103	232	381
3	108	248	443
4	105	241	411
5	105	240	410
Average	105	240	410
St. Dev.	2	2	22
RSD	1,8%	2,4%	5,4%

 

They study authors calculated that:

• < 100 μm: 9.1% v : v, < 10 μm: 0.06% v : v, < 5 μm: 0.02% v : v

Conclusions:

The average d10 was 105 μm, the average d50 was 240 μm, and the average d90 was 410 μm.

Executive summary:

The particle size distribution (PSD) was determined according to NEN-ISO Method 13320-1 and in accordance with European Chemicals Agency (ECHA), Guidance on information requirements and chemical safety assessment, Chapter R.7a, Endpoint specific guidance, May 2008.

 

The PSD characteristics of the sample are reported in the table below.

 

Characteristics of the PSD
d10	105 μm
d50	240 μm
d90	410 μm
Fraction < 100 μm	9.1 % v/v
Fraction < 10 μm	0.06 % v/v
Fraction < 5 μm	0.02 % v/v

 

Description of key information

The particle size distribution (PSD) was determined according to NEN-ISO Method 13320-1.

Additional information

The average d10 was 105 μm, the average d50 was 240 μm, and the average d90 was 410 μm. Approximately 9.1% v:v. of particles were <100 μm, 0.06% v:v. were <10 μm and 0.02% v:v. were < 5 μm.