Registration Dossier
Registration Dossier
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EC number: 907-131-0 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- According to BASF-internal standard
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 3,6,9-trioxaundecane-1,11-diol
- EC Number:
- 203-989-9
- EC Name:
- 3,6,9-trioxaundecane-1,11-diol
- Cas Number:
- 112-60-7
- Molecular formula:
- C8H18O5
- IUPAC Name:
- 2,2'-[oxybis(ethane-2,1-diyloxy)]diethanol
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Purity about 90%
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: Mean body weight of male animals was 190 g, mean body weight of female animals was 170 g.
- Diet: A standard animal diet (Altromin R 1324, Altromin GmbH, Lage, Germany) was used; water was available ad libitum.
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 10000 µL/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 14 days
- Necropsy of survivors performed: yes
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 other: µL/kg
- Based on:
- test mat.
- Remarks on result:
- other: Equivalent to > 11240 mg/kg bw
- Mortality:
- none
- Clinical signs:
- other: no abnormalities
- Gross pathology:
- no abnormalities
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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