Registration Dossier
Registration Dossier
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EC number: 203-542-8 | CAS number: 108-01-0
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic
degradation:
In
the atmosphere the substance 2-dimethylaminoethanol will be
photodegraded rapidly with a half life of 4.618 hours (for a 24 hours
day) (Chemservice S.A., 2010, revised 2019). It is not expected that the
substance will accumulate in the air or be transported in the gaseous
phase over long distances. However, hydrolysis of the substance is not
expected under environmental conditions.
Biodegradation:
The
substance 2 -dimethylaminoethanol was found to be readily biodegradable
according to the criteria set out by OECD Guideline 301C (JETOC, 1992). Conclusively,
the substance will be degraded when entering the environmental
compartment and therefore will not be persistent.
Bioaccumulation:
Due to the measured logPow of -0.55 for the test substance (BASF AG, 1987), accumulation in organisms is not expected. Such a very low value indicates a lack of bioaccumulation potential. Bioaccumulation is expected for substances possessing a partition coefficient in the range of log Pow 4.5 to 6 according to ECHA Guidance Chapter R.11 (PBT Assessment, June 2017). The low bioaccumulative potential of dimethylaminoethanol is also indicated by the calculated BCF value of 3.162 L/kg wet weight (QSAR prediction using BCFBAF v3.00 as implemented in EPIWIN; Chemservice S.A., 2010, revised 2019).
Adsorption / Desorption:
QSAR predictions were used to calculate the Koc in soil as well as the HLC (Henry´s Law constant) of dimethylaminoethanol (Chemservice S.A., 2010, revised 2019). The QSAR prediction with KOCWIN v2.00 (Koc = 1.224 L/kg as key value, estimation based on MCI method) reveals that the substance possesses no strong binding capacity towards soil. According to Blume (1990), Koc values between 1 and 100 indicate a very weak adsorption potential.
The calculated Henry´s Law constant amounts to 1.8 E-4 Pa*m3*mol-1 at 25 °C (Chemservice S.A., 2010, revised 2019). This value, as well as the key value of the Koc estimation, will be taken into account for the chemical safety assessment (CSA), i.e. PNECsediment and PNECsoil derivation via the equilibrium partitioning method (EPM).
References
Blume, H.-P. (1990) Handbuch des Bodenschutzes, 1st edition, ISBN 978-3609658506. Publisher: Hüthig Jehle, Rehm.
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